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Publications and Fundings

Notable Fundings

1.  General Research Fund (2025) by the Hong Kong Research Grants Council. Role : Co-I

2. Collaborative Research Fund (CRF) 2021 by the Hong Kong Research Grants Council. Role : PC
3. Young Investigator Research Grant 2018 by the National Medical Research Council, Ministry of Health, Singapore. Role: PI

Selected Publications

  1. Du S.Y^., Tung W.L.^, ..et. al. Hor C.H.H.* (2025) RAB23 regulates ACE2 surface dynamics to govern SARS-CoV-2 host cell entry. (in submission) 

  2. Du Y.H., Tung W.L., Wu H.H. et al.,... Tan C.W. & Hor C.H.H.* (2025) Primary cilium and TULP3-dependent ciliary targeting of ACE2 in SARS-CoV-2 tropism. (under review)

  3. Huang A.S., Li A.S.M., & Hor C.H.H.* (2025) Primary cilia in the Mature Brain: Emerging Roles in Alzheimer's Disease Pathogenesis. Frontiers in Cell and Developmental Biology. (under revision)

  4. Leong WY, Tung WL, Wilkie AOM, Hor C.H.H.* (2025) RAB23 loss-of-function mutation causes context-dependent ciliopathy in Carpenter syndrome. PLoS Genetics 21(8): e1011611. https://doi.org/10.1371/journal.pgen.1011611

  5. Chau, Y. Y., Liang, H., Tung, W. L., Hor, C. H. H.*, & Aik, W. S.* (2025). Structural basis for Rab23 activation and a loss-of-function mutation in Carpenter Syndrome. Journal of Biological Chemistry, 301(1).

  6. Ho, W. K., Lum, J. T. S., Lam, T. K., Yip, T. N., Hor, C. H. H., & Leung, K. S. Y*. (2024). Quantifying the effects of chlorine disinfection on microplastics by time-resolved inductively coupled plasma-mass spectrometry. Science of The Total Environment, 954, 176132.

  7. Ho, W., Law, J. C., Lo, J. C., Chng, I. K., Hor, C. H. H., Leung, K. S. Y.* (2022) Sorption Behavior, Speciation, and Toxicity of Microplastic-Bound Chromium in Multisolute Systems. Environmental Science and Technology Letters. https://doi.org/10.1021/acs.estlett.2c00689

  8. Yang Q. J., Wang Z.h., Hor C.H.H., Xiao H. T., Bian Z. X., & Wang J. (2022). Asymmetric synthesis of flavanols via Cu-catalyzed kinetic resolution of chromenes and their anti-inflammatory activity. Science Advances, 8 (22), eabm9603.

  9. M Ye, WQ Huang, ZX Li, CX Wang, T Liu, YZ Chen, CHH Hor, WL Man, WX Ni (2022) An Osmium(VI) Nitride Triggers Mitochondria-induced Oncosis and Apoptosis. Chem. Commun. DOI: 10.1039/D1CC05148B

  10. Lo, J. C. W., Wong, W. L., Hor, C. H. H.* (2021) Efficient and Cost Effective Electroporation Method to Study Primary Cilium-dependent Signaling Pathways in the Granule Cell Precursor. J. Vis. Exp. (177), e63283, doi:10.3791/63283.

  11. CHH Hor*, JCW LO, ALS Cham, WY Leong and EL Goh* (2021) Multifaceted functions of Rab23 on primary cilium- and Hedgehog signaling-mediated cerebellar granule cell proliferation. Journal of Neuroscience. 41 (32) 6850-6863 *Co-corresponding author * Cover article

  12. Zhu, Y., Huang, A., Panczuk, T., Hor, C. H. H.*, Wong, K. L.*, & Li, L*. (2021). Persistent luminescence induced by the introduction of multi-valent Mn ions in K2LiBF6 (B= Al, Ga and In) fluoride phosphors. Chemical Engineering Journal, 132421.

  13. CHH Hor and EL Goh (2019) Small GTPases in Hedgehog signaling: emerging insights into the disease mechanism of ciliopathies. Current Opinion in Genetics & Development. 56, 61-68

  14. CW Tan, CHH Hor, SS Kwek, IC Sam, YF Chan, EL Goh, EE Ooi, LF Wang. (2019) Cell surface α2,3-linked sialic acid facilitates Zika virus internalization. Emerging Microbes and Infections. 8 (1), 426-437

  15. CHH Hor and BL Tang. (2019) Beta-propeller protein-associated neurodegeneration (BPAN) as a genetically simple model of multifaceted neuropathology resulting from defects in autophagy. Reviews in the neurosciences. 30(3), 261-277

  16. CHH Hor and EL Goh (2018) Rab23 regulates radial migration of projection neurons via N-cadherin. Cerebral Cortex, 28(4), 1516-1531. Cover article.

  17. CHH Hor*, BL Tang and EL Goh* (2018) Rab23 and developmental disorders. Reviews in the neurosciences. 29 (8) 849-860 *Co-corresponding author

  18. W Pan, HH Hor, CC Hui, MH Sham (2017) Regulation of mammalian hindbrain neural progenitor proliferation and differentiation by Suppressor of fused and β-catenin. Mechanisms of Dev 145, S123

  19. CHH Hor, H Liou and EL Goh (2017) Rab23 Regulates Radial Migration of Projection Neurons via PDGFRα-Mediated Expression of N-cadherin. Mechanisms of Dev 145, S118.

  20. T Ng, CHH Hor, B Chew, J Zhao, Z Zhong, JR Ryu, and EL Goh (2016) Neuropilin 2 signaling is involved in cell positioning of adult-born neurons through GSK3b. J Biol. Chem., 291(48): 25088-25095.

  21. Y Chen, HH Hor and BL Tang (2012) AMIGO is expressed in multiple brain cell types and may regulate dendritic growth and neuronal survival. J Cell Physiol. 227(5), 2217-2229.

Our work was featured on the cover page on The Journal of Neuroscience.  

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Cover Picture: Co-staining of GFP(green), Ki67 (red) and EdU (white) with nuclei marker (DAPI, blue) on brain sections obtained from animals subjected to 24 hours EdU-pulse show migration defects but no change in cell cycle exit in Rab23 knockdown cortical neurons (right column) as compared to controls (left column). See Hor and Goh 2018. Rab23 regulates radial migration of projection neurons via N-cadherin. Cereb Cortex 28(4): 1516-1531.

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